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2013 Annual Report

2013 Annual Report

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Sandler Asthma Basic Research Center

Mission Statement

The Sandler Asthma Basic Research Center (SABRE Center) at UCSF is an investigative unit dedicated to basic discovery in asthma research. The SABRE Center is nucleated by a small group of basic scientists who are supported by advanced technology cores. A monthly seminar series promotes integration of the SABRE Center into the more extended UCSF research community to facilitate collaboration and to increase awareness for needs in fundamental discovery in asthma research.

Founded in 1999, the SABRE Center is made possible by the generous support of the Sandler Foundation.

Summary of Accomplishments over the Past Year

The SABRE Center is maturing into a successful research enterprise embedded within the greater UCSF scientific community. Notable benchmarks achieved this year include: (1) promotion of our first recruit, Dr. Liu, to tenure at UCSF, establishing the center as a successful base for academic advancement; (2) procurement of the first SABRE Center Program Project grant devoted to human asthma research and integration of basic investigators in the SABRE Center with translational investigators in the Airway Clinical Research Center; and (3) a fifth straight year with a continued rise in extramural funds secured by SABRE Center scientists. Investigators have published in competitive and scientifically visible journals and continue to open up novel lines of inquiry into the understanding of asthma and allergy pathogenesis. Interactions with our clinical colleagues in the Pulmonary Division who care for asthma patients are increasing in robust ways. We look forward to further successes in the coming year as we continue with our mission to conquer asthma.

Hot Off the Press

Esteban Burchard, one of our SABRe Core Directors was featured in a recent article, titled "Asthma Treatment May Be Headed Toward Personalized Medicine. Click here to access it.

We recently had a paper published online at Science Express, titled "Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis." To access the abstract or the entire article, please click on the following links.

Abstract
Full Text Article